Creamy Buffalo Chicken Lasagna

This creamy buffalo chicken lasagna roll up recipe blends the bold tang of hot sauce with smooth, cheesy comfort in every bite. The buffalo alfredo sauce draped over tender noodles makes it a flavorful twist on traditional lasagna that keeps weeknight dinners exciting and satisfying.

I first made this for a casual gathering with friends and it quickly became a repeat request because everyone loved the rich sauce and the fun rolled presentation.

Ingredients List

• Lasagna noodles: cook to just al dente to prevent mushy layers upon baking
• Rotisserie chicken breast: shredded for ease and flavor
• Cream cheese: softened to add smoothness and richness
• Mozzarella cheese: shredded for gooey melting texture
• Garlic powder: infuses a subtle depth of flavor
• Onion powder: enhances savory notes
• Chives: chopped fresh for a mild oniony brightness
• Salt: adjusts seasoning to taste
• Alfredo sauce: creamy base that balances heat from buffalo sauce
• Louisiana hot sauce: adds the classic bold buffalo heat and tang
• Chives: pick fresh chives with vibrant green color and fragrant aroma for best flavor

Cooking Steps

Prepare The Oven and Noodles:

Preheat your oven to 375 degrees Fahrenheit. Bring a large pot of water to a boil and salt it well to season the pasta. Cook the lasagna noodles until they are al dente, firm but tender, then drain and spread them out flat on a sheet to cool preventing sticking.

Make The Chicken Filling:

Mix shredded rotisserie chicken with softened cream cheese, half of the shredded mozzarella, garlic powder, onion powder, chopped chives, and salt until fully combined into a creamy, flavorful filling.

Create The Buffalo Alfredo Sauce:

In a separate bowl, stir together the jarred Alfredo sauce with the Louisiana hot sauce until the sauce is a smooth, spicy blend ready to coat the roll ups.

Roll Up The Lasagna:

Spread the chicken mixture evenly over each cooled lasagna noodle, then roll tightly from one end to the other. Pour half of the buffalo Alfredo sauce into the baking dish to coat the bottom.

Arrange And Bake The Rolls:

Place the lasagna rolls standing up in rows in the dish. Pour the remaining buffalo Alfredo sauce over the top, sprinkle the remaining mozzarella cheese generously over everything, then cover loosely with foil.

Bake Covered And Uncovered:

Bake the rolls covered for twenty minutes to melt the cheese and heat through, then uncover and bake an additional ten minutes to brown the top perfectly. Let the dish rest for a few minutes before serving.

I love how the buffalo Alfredo sauce brings a unique creamy heat that my family can't get enough of. Every time I make this it reminds me of fun game nights filled with laughter and good food.

Best Storage Practices

Store any leftovers in an airtight container in the refrigerator for up to three days. The roll ups reheat beautifully in the oven or microwave just until warmed through, preserving their creamy texture without drying out. Avoid freezing as the cream cheese and sauce textures can change.

Ingredient Swaps

Chicken thighs can be shredded in place of rotisserie breast for a richer meat flavor Cream cheese can be substituted with mascarpone for an even silkier filling Use a homemade Alfredo sauce if you prefer to control dairy content or spice level Swap mozzarella with provolone or fontina for a different cheese profile

Serving Pairings

Serve with a crisp green salad tossed in lemon vinaigrette to balance the richness A side of steamed broccoli or roasted asparagus makes a colorful, healthy contrast Garlic bread or cheesy breadsticks complement the lasagna rolls for extra satisfaction

This recipe has become a well-loved staple in my kitchen because it combines comfort and excitement effortlessly. The creamy sauce with spicy buffalo notes keeps everyone coming back for seconds and makes weeknight meals a little more special.

Frequently Asked Cooking Questions

→ How should I cook the lasagna noodles for best results?

Boil the noodles until al dente to prevent them from becoming too soft or mushy when baked. Drain and spread them out on a sheet to cool before filling.

→ Can I adjust the spiciness of this dish?

Yes, you can increase or reduce the amount of hot sauce mixed into the Alfredo to control the level of heat according to your taste.

→ What type of cheese works best in the filling?

A combination of cream cheese and mozzarella creates a creamy, melty texture that complements the shredded chicken and spices well.

→ Is there a way to make the sauce richer?

Using a high-quality Alfredo sauce adds depth and richness that enhances the buffalo flavor in the sauce blend.

→ How do I assemble the rolls for even cooking?

Spread the filling evenly on each noodle, roll tightly, and arrange the rolls standing upright in rows in the baking dish to ensure uniform heat distribution.